RAX

Across TCGA pan-cancer cohorts, RAX mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RAX data layer compared with 18 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RAX mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RAX expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

UCEC, HNSC, and PDAC are the cancer types where RAX mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	All	0.815	1.000	.036	4	view →
HNSC	DFS	Tertile	III,IV	0.905	0.661	.047	2	view →
PDAC	DFS	Median	II,III,IV	0.493	0.338	.026	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RAX–UCEC (OS)

Open the UCEC breakdown →