RAX

Across TCGA patient cohorts, RAX protein abundance is significantly associated with the RNA expression of many other genes, with 3,440 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RAX-associated genes across cancer lineages are NDRG1, CSF3R, and ADGRE3. Each is linked with RAX in more than 1 cancer types. Because this analysis shows association rather than direction, both RAX-to-partner and partner-to-RAX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAX versus NDRG1 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAX→partner) and Y-score (partner→RAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NDRG1 →	+1.154	+0.656	<.001	.001	3	2
PDAC	CSF3R →	-1.225	-1.396	<.001	<.001	3	2
PDAC	ADGRE3 →	-0.965	-1.070	<.001	.001	3	2
GBM	CLDN11 →	+1.076	+0.447	.005	.007	3	2
LSCC	SPRY2 →	+1.400	+0.607	.006	.003	3	2
HNSC	CPEB2 →	+0.665	+0.696	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,440 associations by consensus.

RAX vs NDRG1 — GBM

Explore this scatter interactively →