RAX

Across TCGA cell cohorts, RAX RNA expression is significantly associated with the go_rna of many other GO terms, with 1,965 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAX-associated GO terms across cancer lineages are Negative regulation of vitamin D biosynthetic process, Pantothenate metabolic process, and Positive regulation of cell chemotaxis to fibroblast growth factor. Each is linked with RAX in more than 3 cancer types. Because this analysis shows association rather than direction, both RAX-to-partner and partner-to-RAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of vitamin D biosynthetic process grouped by RAX-low versus RAX-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAX→partner) and Y-score (partner→RAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of vitamin D biosynthetic process →	-1.071	-1.868	<.001	<.001	3	4
BONE	Pantothenate metabolic process →	+0.104	+2.009	<.001	<.001	3	4
BONE	Positive regulation of cell chemotaxis to fibroblast growth factor →	-1.165	-2.094	<.001	<.001	3	4
BONE	Positive regulation of endothelial cell chemotaxis to fibroblast growth factor →	-1.165	-2.094	<.001	<.001	3	4
BONE	Positive regulation of nucleobase-containing compound transport →	+0.109	+1.958	<.001	<.001	3	4
BONE	Regulation of centrosome cycle →	+0.091	+2.454	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,965 associations by consensus.

Negative regulation of vitamin D biosynthetic process by RAX expression — BONE

Explore this box plot interactively →