RAX

Across TCGA cell cohorts, RAX mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAX-associated genes across cancer lineages are ZP2 and CR1. Each is linked with RAX in more than 1 cancer types. Because this analysis shows association rather than direction, both RAX-to-partner and partner-to-RAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP2 grouped by RAX-low versus RAX-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAX→partner) and Y-score (partner→RAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZP2 →	+0.143	+3.678	.001	.009	3	1
LARGE_INTESTINE	CR1 →	+0.016	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ZP2 by RAX expression — LARGE_INTESTINE

Explore this box plot interactively →