RAVER1

Across TCGA patient cohorts, RAVER1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,667 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAVER1-associated genes across cancer lineages are QTRT1, ECSIT, and MRPL4. Each is linked with RAVER1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RAVER1-to-partner and partner-to-RAVER1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAVER1 versus QTRT1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAVER1→partner) and Y-score (partner→RAVER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	QTRT1 →	+0.977	+0.178	<.001	<.001	3	8
HNSC	ECSIT →	+0.865	+0.191	<.001	<.001	3	8
BRCA	MRPL4 →	+0.861	+0.292	<.001	<.001	3	7
OV	TNPO2 →	+0.780	+0.364	.001	.001	3	7
UCEC	GCDH →	+0.773	+0.185	<.001	<.001	3	7
UCEC	TRIR →	+0.913	+0.168	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,667 associations by consensus.

RAVER1 vs QTRT1 — UCEC

Explore this scatter interactively →