RAVER1

Across TCGA cell cohorts, RAVER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,782 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RAVER1-associated GO terms across cancer lineages are Regulation of protein localization to chromatin, Chromosome condensation, and Positive regulation of nuclear cell cycle DNA replication. Each is linked with RAVER1 in more than 18 cancer types. Because this analysis shows association rather than direction, both RAVER1-to-partner and partner-to-RAVER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to chromatin grouped by RAVER1-low versus RAVER1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAVER1→partner) and Y-score (partner→RAVER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein localization to chromatin →	+0.135	+0.994	.001	<.001	3	19
BONE	Chromosome condensation →	+0.209	+1.213	.001	<.001	3	19
BONE	Positive regulation of nuclear cell cycle DNA replication →	+0.168	+1.017	.003	.005	3	18
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.101	+1.076	.002	<.001	3	18
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.254	+1.553	<.001	<.001	3	18
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.196	+1.162	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,782 associations by consensus.

Regulation of protein localization to chromatin by RAVER1 expression — BONE

Explore this box plot interactively →