Across TCGA cell cohorts, RASSF9 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASSF9-associated genes across cancer lineages are Afatinib, LCL161, and WYE-125132. Each is linked with RASSF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASSF9-to-partner and partner-to-RASSF9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF9→partner) and Y-score (partner→RASSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Afatinib →	+0.548	+2.868	.045	.022	3	1
LARGE_INTESTINE	LCL161 →	+0.318	+2.868	.040	.022	3	1
LARGE_INTESTINE	WYE-125132 →	+0.668	+2.652	.008	.045	3	1
LARGE_INTESTINE	AST-1306 →	+0.626	+2.684	.004	.035	3	1
LARGE_INTESTINE	UNC0642 →	+0.192	+2.881	.031	.019	2	1
LARGE_INTESTINE	PF-00299804 →	+0.652	+2.652	.004	.045	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

RASSF9 survival (RNA) · tumor vs normal (RNA) · all RASSF9 data types