RASSF8

Across TCGA cell cohorts, RASSF8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,122 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RASSF8-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Regulation of cytokinesis, and Positive regulation of cell-substrate junction organization. Each is linked with RASSF8 in more than 14 cancer types. Because this analysis shows association rather than direction, both RASSF8-to-partner and partner-to-RASSF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by RASSF8-low versus RASSF8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF8→partner) and Y-score (partner→RASSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.279	+1.815	<.001	<.001	3	15
STOMACH	Regulation of cytokinesis →	+0.060	+2.416	<.001	.001	3	13
BONE	Positive regulation of cell-substrate junction organization →	+0.216	+1.638	<.001	<.001	3	13
BONE	Regulation of cell-substrate junction organization →	+0.141	+1.435	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Negative regulation of beige fat cell differentiation →	+0.165	+1.854	.002	.003	3	12
STOMACH	Protein deneddylation →	+0.135	+3.514	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,122 associations by consensus.

Positive regulation of focal adhesion assembly by RASSF8 expression — BONE

Explore this box plot interactively →