RASSF8-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RASSF8-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RASSF8-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RASSF8-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RASSF8-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and UCS show a favorable association.

MESO, UCS, and LUSC are the cancer types where RASSF8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileAll0.5320.256<.00171view →
UCSOSMedianIII,IV0.6720.239.00152view →
LUSCDFSMedianIII,IV0.5420.767.00351view →
PAADOSTertileAll0.5940.279<.00141view →
KIRCDFSMedianII,III,IV0.6300.751.00240view →
KIRPDFSMedianIV0.6850.040.00237view →
STADOSTertileAll0.5840.830.00433view →
BRCADFSQuartileIII,IV0.8690.689.00332view →
SKCMDFSMedianII,III,IV0.2770.174.00228view →
KICHOSQuartileAll0.3961.000<.00122view →
LGGOSQuartileAll0.7140.945<.00122view →
ACCDFSQuartileAll0.6590.929.01918view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RASSF8-AS1–MESO (OS)

Kaplan–Meier survival curve for RASSF8-AS1 RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration