RASSF7

Across TCGA pan-cancer cohorts, RASSF7 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RASSF7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RASSF7 RNA is repressed in tumor relative to normal tissue. In most cancer types RASSF7 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KICH, LIHC, and BLCA are the cancer types where RASSF7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RASSF7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.601	<.001	9	view →
LIHC	All	III,IV	+1.144	<.001	9	view →
BLCA	All	All	+2.054	<.001	8	view →
COAD	All	All	+0.560	<.001	8	view →
STAD	All	All	+1.685	<.001	6	view →
BRCA	All	III,IV	+1.350	<.001	6	view →
CHOL	All	All	+2.370	<.001	5	view →
LUSC	All	All	−0.660	<.001	5	view →
PAAD	All	All	+1.512	.013	4	view →
THCA	All	All	+0.312	.002	4	view →
HNSC	Male	All	+0.612	.015	3	view →
UCEC	All	All	+1.313	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RASSF7–KICH

Open the KICH breakdown →