RASSF2

Across TCGA cell cohorts, RASSF2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASSF2-associated genes across cancer lineages are GAGE12J, TBL1Y, and CSN2. Each is linked with RASSF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASSF2-to-partner and partner-to-RASSF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12J grouped by RASSF2-low versus RASSF2-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF2→partner) and Y-score (partner→RASSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
LARGE_INTESTINE	CSN2 →	+0.024	+4.684	.003	.002	3	1
LARGE_INTESTINE	CBLL2 →	+0.015	+4.467	.001	.004	3	1
LARGE_INTESTINE	F11 →	+0.057	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GAGE12J by RASSF2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →