Across TCGA pan-cancer cohorts, RASSF10 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RASSF10’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where RASSF10 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types RASSF10 is over-expressed in tumor, although a few such as CCRCC show the opposite, repressed pattern.

CCRCC and LSCC are the cancer types where RASSF10 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RASSF10 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	All	All	−0.839	.001	5	view →
LSCC	All	All	+0.473	.006	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RASSF10 RNA expression & survival · all RASSF10 data types