RASL12

Across TCGA patient cohorts, RASL12 mutation is significantly associated with the RNA expression of many other genes, with 1,198 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASL12-associated genes across cancer lineages are CSGALNACT2P2, MIR7845, and RNY4P13. Each is linked with RASL12 in more than 2 cancer types. Because this analysis shows association rather than direction, both RASL12-to-partner and partner-to-RASL12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSGALNACT2P2 grouped by RASL12-low versus RASL12-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL12→partner) and Y-score (partner→RASL12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSGALNACT2P2 →	+0.185	+6.251	<.001	.001	3	3
BRCA	MIR7845 →	+0.399	+4.500	.007	.005	3	2
LUAD	RNY4P13 →	+0.670	+5.157	<.001	.007	3	2
UCEC	FANCA →	+0.700	+2.601	<.001	.006	3	2
UCEC	ZFP57 →	+0.303	+3.275	.004	.008	3	2
UCEC	SNORD90 →	+0.232	+2.255	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,198 associations by consensus.

CSGALNACT2P2 by RASL12 expression — COAD

Explore this box plot interactively →