RASL11B

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RASL11B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RASL11B data layer compared with 27 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RASL11B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RASL11B expression acts as an unfavorable survival marker.

LUSC and STAD are the cancer types where RASL11B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSMedianII,III,IV0.1390.663.0276view →
STADOSMedianAll0.2500.729.0286view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RASL11B–LUSC (DFS)

Kaplan–Meier survival curve for RASL11B mutant vs wild-type samples in LUSC.

Open the LUSC breakdown →

Exploration