RASL11B

Across TCGA patient cohorts, RASL11B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASL11B-associated genes across cancer lineages are mv Endothelial cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with RASL11B in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL11B-to-partner and partner-to-RASL11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by RASL11B-low versus RASL11B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL11B→partner) and Y-score (partner→RASL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mv Endothelial cells →	-0.030	-3.000	.014	.036	3	1
UCEC	Endothelial cells →	-0.045	-3.279	.023	.011	2	1
UCEC	lymphatic Endothelial cells →	-0.026	-3.268	.033	.011	2	1
UCEC	Th2 cells →	+0.258	+3.177	.006	.010	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

mv Endothelial cells by RASL11B expression — UCEC

Explore this box plot interactively →