RASL11B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RASL11B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,756 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RASL11B-associated GO terms across cancer lineages are Cell cycle phase transition, Purine nucleotide biosynthetic process, and Nucleotide biosynthetic process. Each is linked with RASL11B in more than 8 cancer types. Because this analysis shows association rather than direction, both RASL11B-to-partner and partner-to-RASL11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle phase transition grouped by RASL11B-low versus RASL11B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL11B→partner) and Y-score (partner→RASL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUECell cycle phase transition →+0.109+1.924<.001<.00139
OESOPHAGUSPurine nucleotide biosynthetic process →+0.096+0.841.002.00138
LUNG_NSCLC_LUSCNucleotide biosynthetic process →+0.089+1.728.007.00938
SOFT_TISSUENegative regulation of translational elongation →+0.179+1.958<.001<.00138
LUNG_NSCLC_LUADTranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →+0.086+0.535<.001<.00138
LUNG_NSCLC_LUSCRegulation of nucleotide-excision repair →+0.122+2.409<.001.00437
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,756 associations by consensus.

Cell cycle phase transition by RASL11B expression — SOFT_TISSUE

Box plot of Cell cycle phase transition in RASL11B-low vs RASL11B-high samples in SOFT_TISSUE.

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Exploration