RASL11B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RASL11B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASL11B-associated genes across cancer lineages are ZNF831, TAFA1, and CENPVL1. Each is linked with RASL11B in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL11B-to-partner and partner-to-RASL11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF831 grouped by RASL11B-low versus RASL11B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL11B→partner) and Y-score (partner→RASL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEZNF831 →+0.018+4.273<.001.00631
LARGE_INTESTINETAFA1 →+0.410+4.273<.001.00631
LARGE_INTESTINECENPVL1 →+0.227+4.095<.001.00931
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ZNF831 by RASL11B expression — LARGE_INTESTINE

Box plot of ZNF831 in RASL11B-low vs RASL11B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration