RASL10B

Across TCGA patient cohorts, RASL10B mutation is significantly associated with the RNA expression of many other genes, with 2,466 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASL10B-associated genes across cancer lineages are FGFR3P6, RNA5SP419, and RNU6-104P. Each is linked with RASL10B in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL10B-to-partner and partner-to-RASL10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGFR3P6 grouped by RASL10B-low versus RASL10B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL10B→partner) and Y-score (partner→RASL10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	FGFR3P6 →	+0.194	+5.978	<.001	.002	3	2
CESC	RNA5SP419 →	+0.201	+5.579	<.001	.001	3	2
SKCM	RNU6-104P →	+0.183	+4.147	<.001	.008	3	2
LUAD	VTRNA2-2P →	+0.484	+5.554	<.001	.004	3	2
SKCM	BOLA3P3 →	+0.208	+3.866	.005	.002	3	2
UCEC	MIR6803 →	+0.162	+4.671	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,466 associations by consensus.

FGFR3P6 by RASL10B expression — LUSC

Explore this box plot interactively →