RASL10B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RASL10B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,065 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RASL10B-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of double-strand break repair, and Positive regulation of double-strand break repair. Each is linked with RASL10B in more than 15 cancer types. Because this analysis shows association rather than direction, both RASL10B-to-partner and partner-to-RASL10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by RASL10B-low versus RASL10B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL10B→partner) and Y-score (partner→RASL10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCEpigenetic regulation of gene expression →+0.078+2.371<.001<.001316
OVARYRegulation of double-strand break repair →+0.064+1.269<.001.006314
SOFT_TISSUEPositive regulation of double-strand break repair →+0.071+1.516.004<.001314
OESOPHAGUSRNA splicing, via transesterification reactions →+0.094+2.041<.001<.001314
OESOPHAGUSRNA splicing, via transesterification reactions with bulged adenosine as nucleophile →+0.093+2.041<.001<.001314
OESOPHAGUSmRNA splicing, via spliceosome →+0.093+2.041<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,065 associations by consensus.

Epigenetic regulation of gene expression by RASL10B expression — LUNG_SCLC

Box plot of Epigenetic regulation of gene expression in RASL10B-low vs RASL10B-high samples in LUNG_SCLC.

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Exploration