RASL10B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RASL10B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASL10B-associated genes across cancer lineages are MAGEB4 and CCDC195. Each is linked with RASL10B in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL10B-to-partner and partner-to-RASL10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by RASL10B-low versus RASL10B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL10B→partner) and Y-score (partner→RASL10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMAGEB4 →+0.016+4.415<.001<.00131
LARGE_INTESTINECCDC195 →+0.054+3.882<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MAGEB4 by RASL10B expression — LARGE_INTESTINE

Box plot of MAGEB4 in RASL10B-low vs RASL10B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration