RASIP1

Across TCGA pan-cancer cohorts, RASIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RASIP1 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RASIP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RASIP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where RASIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.782	1.000	.002	38	view →
CCRCC	DFS	Quartile	III,IV	0.821	0.329	.002	21	view →
HNSC	OS	Median	All	1.000	0.484	.038	12	view →
LSCC	DFS	Median	All	0.894	0.976	.026	4	view →
PDAC	DFS	Tertile	IV	0.752	0.203	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RASIP1–LUAD (OS)

Open the LUAD breakdown →