RASIP1

Across TCGA cell cohorts, RASIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,341 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RASIP1-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Regulation of RNA splicing, and Positive regulation of matrix metallopeptidase secretion. Each is linked with RASIP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RASIP1-to-partner and partner-to-RASIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by RASIP1-low versus RASIP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASIP1→partner) and Y-score (partner→RASIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.092	+0.627	.001	.009	2	7
BLOOD_Leukemia	Regulation of RNA splicing →	+0.031	+0.545	.008	.003	3	6
LUNG_SCLC	Positive regulation of matrix metallopeptidase secretion →	+0.179	+1.057	.002	.003	3	6
BONE	Locomotory exploration behavior →	+0.175	+0.752	<.001	<.001	3	6
BONE	Sperm-egg recognition →	-0.274	-0.954	<.001	<.001	3	6
BONE	Trans-synaptic signaling by BDNF, modulating synaptic transmission →	-1.017	-0.631	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,341 associations by consensus.

Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by RASIP1 expression — OESOPHAGUS

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