RASGRP3-AS1

Across TCGA pan-cancer cohorts, RASGRP3-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RASGRP3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RASGRP3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RASGRP3-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and READ show a favorable association.

KIRC, BRCA, and UVM are the cancer types where RASGRP3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.509	0.725	<.001	117	view →
BRCA	DFS	Tertile	All	0.858	0.936	<.001	77	view →
UVM	DFS	Quartile	All	0.330	0.940	<.001	37	view →
OV	OS	Median	III,IV	0.276	0.359	.018	30	view →
MESO	OS	Quartile	II,III,IV	0.254	0.523	.002	29	view →
KIRP	OS	Tertile	III,IV	0.500	0.802	.008	26	view →
PAAD	OS	Median	II,III,IV	0.641	0.359	.002	23	view →
READ	DFS	Median	II,III,IV	0.856	0.489	<.001	20	view →
LGG	DFS	Tertile	All	0.794	0.892	.002	18	view →
PRAD	DFS	Tertile	All	0.853	0.937	.009	16	view →
ACC	OS	Tertile	III,IV	0.150	0.741	.003	14	view →
ESCA	OS	Median	All	0.617	1.000	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RASGRP3-AS1–KIRC (OS)

Open the KIRC breakdown →