RASGRP1

Across TCGA patient cohorts, RASGRP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,603 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RASGRP1-associated proteins across cancer lineages are ANKRD44, CORO1A, and DEF6. Each is linked with RASGRP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RASGRP1-to-partner and partner-to-RASGRP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASGRP1 versus ANKRD44 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRP1→partner) and Y-score (partner→RASGRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ANKRD44 →	+0.434	+0.709	<.001	<.001	3	8
CCRCC	CORO1A →	+0.548	+0.981	<.001	<.001	3	8
CCRCC	DEF6 →	+0.504	+0.799	<.001	<.001	3	8
HNSC	EVL →	+0.869	+0.773	<.001	<.001	3	8
UCEC	WAS →	+0.625	+0.862	<.001	<.001	3	7
HNSC	IL16 →	+0.781	+0.904	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,603 associations by consensus.

RASGRP1 vs ANKRD44 — HNSC

Explore this scatter interactively →