RASGRP1

Across TCGA cell cohorts, RASGRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,847 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RASGRP1-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with RASGRP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both RASGRP1-to-partner and partner-to-RASGRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by RASGRP1-low versus RASGRP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRP1→partner) and Y-score (partner→RASGRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoplasmic translation →	+0.086	+1.671	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.107	+0.442	.001	.004	2	12
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.097	+1.068	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.080	+0.503	.009	.004	1	11
BONE	Nucleobase-containing compound transport →	+0.048	+0.152	.004	<.001	2	10
BLOOD_Lymphoma	Cytosolic transport →	+0.037	+1.356	.007	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,847 associations by consensus.

Cytoplasmic translation by RASGRP1 expression — LUNG_SCLC

Explore this box plot interactively →