RASGRF2-AS1

Across TCGA pan-cancer cohorts, RASGRF2-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RASGRF2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RASGRF2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RASGRF2-AS1 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

KIRP, THCA, and LIHC are the cancer types where RASGRF2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RASGRF2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	−0.223	<.001	9	view →
THCA	All	II,III,IV	−0.386	<.001	8	view →
LIHC	Female	All	+0.119	<.001	8	view →
BLCA	All	All	−0.193	.006	7	view →
BRCA	All	III,IV	−0.425	<.001	6	view →
LUAD	Female	All	+0.249	<.001	5	view →
UCEC	All	All	−0.349	.003	4	view →
KIRC	All	All	+0.112	.004	4	view →
COAD	All	All	+0.112	.017	3	view →
HNSC	Female	II,III,IV	+0.093	.037	2	view →
LUSC	Female	All	−0.146	.023	1	view →
CHOL	All	All	+0.092	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RASGRF2-AS1–KIRP

Open the KIRP breakdown →