RASGEF1B

Across TCGA patient cohorts, RASGEF1B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,922 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RASGEF1B-associated proteins across cancer lineages are CTSS, EVL, and TNFAIP8. Each is linked with RASGEF1B in more than 6 cancer types. Because this analysis shows association rather than direction, both RASGEF1B-to-partner and partner-to-RASGEF1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASGEF1B versus CTSS in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGEF1B→partner) and Y-score (partner→RASGEF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTSS →	+0.546	+0.872	<.001	<.001	3	6
HNSC	EVL →	+0.569	+0.483	<.001	.009	2	7
GBM	TNFAIP8 →	+0.571	+0.709	<.001	<.001	3	6
COAD	PSMB7 →	-0.307	-0.422	<.001	.005	3	6
GBM	FYB1 →	+0.666	+0.902	<.001	<.001	3	6
GBM	GIMAP4 →	+0.517	+0.728	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,922 associations by consensus.

RASGEF1B vs CTSS — GBM

Explore this scatter interactively →