RASGEF1B

Across TCGA patient cohorts, RASGEF1B protein abundance is significantly associated with the protein abundance of many other proteins, with 17,769 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RASGEF1B-associated proteins across cancer lineages are AUTS2_S1198, C1orf226_S198, and CNKSR2_S430. Each is linked with RASGEF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both RASGEF1B-to-partner and partner-to-RASGEF1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASGEF1B versus AUTS2_S1198 in LSCC, with a Pearson correlation of -0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGEF1B→partner) and Y-score (partner→RASGEF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AUTS2_S1198 →	-0.863	-0.496	.001	<.001	3	1
LSCC	C1orf226_S198 →	-1.867	-0.634	<.001	.004	3	1
LSCC	CNKSR2_S430 →	+0.784	+0.468	.001	.005	3	1
LSCC	P2RY1_S352 →	-0.883	-0.461	.002	.002	3	1
LSCC	PREP_S667 →	+0.593	+0.646	<.001	.003	3	1
LSCC	PRRC2B_S388 →	-0.598	-0.483	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,769 associations by consensus.

RASGEF1B vs AUTS2_S1198 — LSCC

Explore this scatter interactively →