RASGEF1B

Across TCGA cell cohorts, RASGEF1B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,349 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RASGEF1B-associated GO terms across cancer lineages are Dentinogenesis, Protein transport within lipid bilayer, and Negative regulation of stem cell differentiation. Each is linked with RASGEF1B in more than 10 cancer types. Because this analysis shows association rather than direction, both RASGEF1B-to-partner and partner-to-RASGEF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dentinogenesis grouped by RASGEF1B-low versus RASGEF1B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGEF1B→partner) and Y-score (partner→RASGEF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Dentinogenesis →	-2.242	-1.742	<.001	<.001	3	11
LIVER	Protein transport within lipid bilayer →	+0.332	+1.478	<.001	<.001	3	11
LUNG_SCLC	Negative regulation of stem cell differentiation →	+0.202	+2.829	<.001	<.001	3	10
STOMACH	Regulation of thrombin-activated receptor signaling pathway →	-1.688	-1.443	<.001	<.001	3	10
STOMACH	Negative regulation of thrombin-activated receptor signaling pathway →	-1.688	-1.443	<.001	<.001	3	10
STOMACH	Serotonin secretion →	+0.979	+1.170	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,349 associations by consensus.

Dentinogenesis by RASGEF1B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →