RASGEF1A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RASGEF1A mutation is significantly associated with the RNA expression of many other genes, with 2,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASGEF1A-associated genes across cancer lineages are RNY4, RN7SL66P, and LAMTOR1. Each is linked with RASGEF1A in more than 1 cancer types. Because this analysis shows association rather than direction, both RASGEF1A-to-partner and partner-to-RASGEF1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGEF1A→partner) and Y-score (partner→RASGEF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNY4 →+0.498+4.934<.001.00232
BLCARN7SL66P →+0.163+5.177<.001.00732
UCECLAMTOR1 →+0.354+3.708.002<.00132
UCECSLC3A2 →+0.449+1.890.001.00532
SKCMSNORD105B →+0.300+2.743<.001.00832
LUADRNU6-497P →+0.346+5.481<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,023 associations by consensus.

Exploration