Across TCGA cell cohorts, RASGEF1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,799 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RASGEF1A-associated GO terms across cancer lineages are Positive regulation of matrix metallopeptidase secretion, Positive regulation of glycoprotein metabolic process, and Pyrimidine nucleobase metabolic process. Each is linked with RASGEF1A in more than 5 cancer types. Because this analysis shows association rather than direction, both RASGEF1A-to-partner and partner-to-RASGEF1A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGEF1A→partner) and Y-score (partner→RASGEF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of matrix metallopeptidase secretion →	+0.198	+1.404	<.001	.001	3	6
STOMACH	Positive regulation of glycoprotein metabolic process →	+0.108	+1.448	<.001	.001	3	5
STOMACH	Pyrimidine nucleobase metabolic process →	+0.116	+1.955	.001	.001	3	5
LUNG_NSCLC_LUAD	Alcohol metabolic process →	+0.032	+1.156	.004	.001	3	5
BONE	Response to oxygen levels →	+0.069	+0.623	<.001	.005	3	5
LUNG_NSCLC_LUAD	Nucleoside phosphate biosynthetic process →	+0.044	+1.169	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,799 associations by consensus.

Exploration

RASGEF1A survival (RNA) · tumor vs normal (RNA) · all RASGEF1A data types