RASEF

Across TCGA patient cohorts, RASEF RNA expression is significantly associated with the protein abundance of many other proteins, with 13,349 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RASEF-associated proteins across cancer lineages are MYO6, ARFGEF3, and ARHGEF16. Each is linked with RASEF in more than 6 cancer types. Because this analysis shows association rather than direction, both RASEF-to-partner and partner-to-RASEF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASEF versus MYO6 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RASEF→partner) and Y-score (partner→RASEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYO6 →	+0.492	+1.560	<.001	<.001	3	7
UCEC	ARFGEF3 →	+0.465	+0.736	.002	.002	3	6
HNSC	ARHGEF16 →	+0.574	+0.862	<.001	.005	3	6
UCEC	BSPRY →	+0.774	+0.881	<.001	<.001	3	6
GBM	TCEA3 →	+0.747	+1.254	.002	.008	2	7
UCEC	TRIM2 →	+0.674	+0.863	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,349 associations by consensus.

RASEF vs MYO6 — BRCA

Explore this scatter interactively →