RASEF

Across TCGA patient cohorts, RASEF protein abundance is significantly associated with the RNA expression of many other genes, with 5,179 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RASEF-associated genes across cancer lineages are MLPH, KIF13B, and LINC02595. Each is linked with RASEF in more than 3 cancer types. Because this analysis shows association rather than direction, both RASEF-to-partner and partner-to-RASEF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASEF versus MLPH in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASEF→partner) and Y-score (partner→RASEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MLPH →	+2.295	+0.522	<.001	<.001	3	3
BRCA	KIF13B →	+0.993	+0.537	<.001	<.001	3	3
UCEC	LINC02595 →	-1.164	-0.638	.008	.002	2	4
CCRCC	SLC16A8 →	-0.977	-0.917	.009	.005	3	3
BRCA	SEC23B →	+0.460	+0.486	<.001	<.001	3	2
BRCA	CRNKL1 →	+0.447	+0.522	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,179 associations by consensus.

RASEF vs MLPH — BRCA

Explore this scatter interactively →