RASEF

Across TCGA cell cohorts, RASEF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,339 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RASEF-associated GO terms across cancer lineages are Bundle of His cell to Purkinje myocyte communication, Regulation of blood-brain barrier permeability, and Serotonin secretion. Each is linked with RASEF in more than 10 cancer types. Because this analysis shows association rather than direction, both RASEF-to-partner and partner-to-RASEF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell to Purkinje myocyte communication grouped by RASEF-low versus RASEF-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASEF→partner) and Y-score (partner→RASEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.297	+2.082	<.001	<.001	3	11
STOMACH	Regulation of blood-brain barrier permeability →	+0.273	+1.905	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Serotonin secretion →	+1.656	+1.867	<.001	.002	3	10
LUNG_NSCLC_LUSC	Serotonin production involved in inflammatory response →	+1.656	+1.867	<.001	.002	3	10
LUNG_NSCLC_LUSC	Serotonin secretion involved in inflammatory response →	+1.656	+1.867	<.001	.002	3	10
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	-0.268	-2.227	<.001	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

Bundle of His cell to Purkinje myocyte communication by RASEF expression — STOMACH

Explore this box plot interactively →