RASEF

Across TCGA cell cohorts, RASEF mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RASEF-associated genes across cancer lineages are VSX2, TAS2R9, and C20orf85. Each is linked with RASEF in more than 1 cancer types. Because this analysis shows association rather than direction, both RASEF-to-partner and partner-to-RASEF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VSX2 grouped by RASEF-low versus RASEF-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASEF→partner) and Y-score (partner→RASEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	VSX2 →	+0.035	+4.258	<.001	.002	3	1
BLOOD_Leukemia	TAS2R9 →	+0.024	+4.007	.002	.002	3	1
BLOOD_Leukemia	C20orf85 →	+0.015	+3.969	.005	.009	3	1
BLOOD_Leukemia	CST8 →	+0.031	+3.969	<.001	.009	3	1
BLOOD_Leukemia	USP29 →	+0.004	+3.922	<.001	.002	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.099	+3.922	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

VSX2 by RASEF expression — BLOOD_Leukemia

Explore this box plot interactively →