RASAL2

Across TCGA cell cohorts, RASAL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,804 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RASAL2-associated GO terms across cancer lineages are Regulation of focal adhesion assembly, Regulation of cell-substrate junction assembly, and Regulation of cell-substrate junction organization. Each is linked with RASAL2 in more than 15 cancer types. Because this analysis shows association rather than direction, both RASAL2-to-partner and partner-to-RASAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of focal adhesion assembly grouped by RASAL2-low versus RASAL2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASAL2→partner) and Y-score (partner→RASAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of focal adhesion assembly →	+0.176	+1.418	<.001	<.001	3	16
BONE	Regulation of cell-substrate junction assembly →	+0.176	+1.418	<.001	<.001	3	16
BONE	Regulation of cell-substrate junction organization →	+0.158	+1.418	<.001	<.001	3	15
BONE	Positive regulation of intracellular transport →	+0.070	+1.321	.001	<.001	3	15
BONE	Vesicle-mediated transport to the plasma membrane →	+0.072	+1.439	.001	.001	3	14
CNS	Regulation of intracellular transport →	+0.069	+0.899	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,804 associations by consensus.

Regulation of focal adhesion assembly by RASAL2 expression — BONE

Explore this box plot interactively →