RASAL1

Across TCGA cell cohorts, RASAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,953 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RASAL1-associated GO terms across cancer lineages are Negative regulation of bone mineralization involved in bone maturation, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, and Establishment or maintenance of microtubule cytoskeleton polarity. Each is linked with RASAL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RASAL1-to-partner and partner-to-RASAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of bone mineralization involved in bone maturation grouped by RASAL1-low versus RASAL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASAL1→partner) and Y-score (partner→RASAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of bone mineralization involved in bone maturation →	-1.173	-1.642	<.001	<.001	3	10
LUNG_NSCLC_LUSC	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	-0.150	-1.202	.002	.004	3	10
BLOOD_Lymphoma	Establishment or maintenance of microtubule cytoskeleton polarity →	-0.162	-2.071	<.001	<.001	3	10
STOMACH	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.215	+2.865	<.001	<.001	3	9
OESOPHAGUS	Regulation of membrane depolarization during action potential →	+0.125	+1.313	.008	.004	3	9
LUNG_NSCLC_LUSC	Cellular response to alcohol →	+0.107	+0.863	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,953 associations by consensus.

Negative regulation of bone mineralization involved in bone maturation by RASAL1 expression — OVARY

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