Across TCGA pan-cancer cohorts, RASA4CP RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of RASA4CP’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RASA4CP RNA is repressed in tumor relative to normal tissue. In most cancer types RASA4CP is over-expressed in tumor, although a few such as HNSC and UCEC show the opposite, repressed pattern.
HNSC, UCEC, and COAD are the cancer types where RASA4CP tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RASA4CP RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.