RASA4B

Across TCGA pan-cancer cohorts, RASA4B mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RASA4B data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RASA4B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RASA4B expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LUAD, GBM, and LSCC are the cancer types where RASA4B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	1.000	0.308	.025	7	view →
GBM	DFS	Tertile	All	0.567	0.200	.009	4	view →
LSCC	DFS	Median	All	0.546	1.000	.040	2	view →
CCRCC	DFS	Quartile	III,IV	0.690	1.000	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RASA4B–LUAD (OS)

Open the LUAD breakdown →