Across TCGA patient cohorts, RASA3 mutation is significantly associated with the RNA expression of many other genes, with 3,982 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASA3-associated genes across cancer lineages are FARSBP1, OR52M2P, and NIPAL2. Each is linked with RASA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RASA3-to-partner and partner-to-RASA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASA3→partner) and Y-score (partner→RASA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FARSBP1 →	+0.046	+1.613	.001	.005	3	4
BLCA	OR52M2P →	+0.026	+4.814	<.001	.003	3	3
UCEC	NIPAL2 →	-0.395	-1.847	.008	.008	3	3
UCEC	CCDC86 →	+0.524	+1.868	<.001	<.001	3	3
UCEC	FARSB →	+0.303	+1.872	.003	.004	3	3
UCEC	HROB →	+0.611	+2.454	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,982 associations by consensus.

Exploration

RASA3 survival (RNA) · tumor vs normal (RNA) · all RASA3 data types