Across TCGA cell cohorts, RASA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,116 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RASA3-associated GO terms across cancer lineages are Negative regulation of Rho protein signal transduction, Positive regulation of cell-substrate junction organization, and Actin filament depolymerization. Each is linked with RASA3 in more than 13 cancer types. Because this analysis shows association rather than direction, both RASA3-to-partner and partner-to-RASA3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASA3→partner) and Y-score (partner→RASA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of Rho protein signal transduction →	+0.181	+1.701	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate junction organization →	+0.173	+2.307	<.001	<.001	3	13
BONE	Actin filament depolymerization →	+0.192	+2.582	<.001	<.001	3	13
BONE	Negative regulation of small GTPase mediated signal transduction →	+0.091	+1.696	.001	<.001	3	13
BONE	Regulation of cell-substrate junction assembly →	+0.160	+1.992	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Negative regulation of hemostasis →	+0.218	+2.035	.002	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,116 associations by consensus.

Exploration

RASA3 survival (RNA) · tumor vs normal (RNA) · all RASA3 data types