Across TCGA cell cohorts, RASA3 mutation is significantly associated with the RNA expression of many other genes, with 272 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASA3-associated genes across cancer lineages are TMEM252, REG3G, and DNAAF6. Each is linked with RASA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASA3-to-partner and partner-to-RASA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASA3→partner) and Y-score (partner→RASA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TMEM252 →	+0.637	+4.217	<.001	.005	3	2
BLOOD_Lymphoma	REG3G →	+0.033	+3.867	<.001	.002	3	2
BLOOD_Lymphoma	DNAAF6 →	+0.038	+3.534	.002	.008	3	2
LARGE_INTESTINE	PGAP4 →	+1.118	+3.502	.004	.001	3	2
LUNG_NSCLC_LUAD	OR13C9 →	+0.010	+4.681	<.001	.003	3	2
URINARY_TRACT	NPHS2 →	+0.187	+5.044	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 272 associations by consensus.

Exploration

RASA3 survival (RNA) · tumor vs normal (RNA) · all RASA3 data types