RASA2-IT1

Across TCGA pan-cancer cohorts, RASA2-IT1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RASA2-IT1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RASA2-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RASA2-IT1 expression acts as an unfavorable survival marker, although some lineages such as UCS and STAD show a favorable association.

KIRC, THCA, and LIHC are the cancer types where RASA2-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.505	0.698	.002	42	view →
THCA	OS	Tertile	IV	0.558	0.893	.006	36	view →
LIHC	DFS	Tertile	III,IV	0.076	0.360	.001	36	view →
BLCA	DFS	Quartile	II,III,IV	0.417	0.540	.016	27	view →
DLBC	OS	Tertile	All	0.599	1.000	.005	24	view →
SKCM	DFS	Tertile	IV	0.130	0.511	.006	18	view →
OV	DFS	Quartile	IV	0.248	0.565	.003	16	view →
UCS	DFS	Tertile	IV	0.981	0.573	.025	12	view →
STAD	OS	Quartile	IV	0.702	0.309	.022	11	view →
PAAD	DFS	Tertile	III,IV	0.152	0.821	.045	9	view →
CESC	OS	Quartile	All	0.710	0.821	.019	6	view →
ESCA	OS	Median	III,IV	0.601	0.316	.002	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RASA2-IT1–KIRC (DFS)

Open the KIRC breakdown →