RASA1

Across TCGA cell cohorts, RASA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,900 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RASA1-associated GO terms across cancer lineages are Regulation of hippo signaling, Regulation of focal adhesion assembly, and Regulation of cell-substrate junction assembly. Each is linked with RASA1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RASA1-to-partner and partner-to-RASA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippo signaling grouped by RASA1-low versus RASA1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASA1→partner) and Y-score (partner→RASA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of hippo signaling →	+0.073	+1.230	.002	.002	3	14
BONE	Regulation of focal adhesion assembly →	+0.176	+1.353	<.001	<.001	3	14
BONE	Regulation of cell-substrate junction assembly →	+0.176	+1.353	<.001	<.001	3	14
BONE	Regulation of cell-substrate junction organization →	+0.116	+0.912	<.001	<.001	3	13
BREAST	Endosomal transport →	+0.066	+1.081	<.001	<.001	3	13
BONE	Regulation of cell-matrix adhesion →	+0.163	+1.312	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,900 associations by consensus.

Regulation of hippo signaling by RASA1 expression — KIDNEY

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