RARS2

Across TCGA patient cohorts, RARS2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,195 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RARS2-associated genes across cancer lineages are IFFO1, MEOX2, and ZEB1. Each is linked with RARS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both RARS2-to-partner and partner-to-RARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RARS2 versus IFFO1 in LSCC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RARS2→partner) and Y-score (partner→RARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IFFO1 →	-0.585	-0.233	<.001	.001	3	5
HNSC	MEOX2 →	-1.239	-0.279	<.001	.001	3	5
BRCA	ZEB1 →	-0.886	-0.180	<.001	<.001	3	5
BRCA	JAM2 →	-0.786	-0.289	<.001	<.001	3	5
LSCC	ANTXR2 →	-0.643	-0.227	<.001	<.001	3	5
UCEC	LMOD1 →	-1.350	-0.251	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,195 associations by consensus.

RARS2 vs IFFO1 — LSCC

Explore this scatter interactively →