RARS2

Across TCGA cell cohorts, RARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,014 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RARS2-associated GO terms across cancer lineages are 7-methylguanosine mRNA capping, 7-methylguanosine RNA capping, and 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process. Each is linked with RARS2 in more than 15 cancer types. Because this analysis shows association rather than direction, both RARS2-to-partner and partner-to-RARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 7-methylguanosine mRNA capping grouped by RARS2-low versus RARS2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RARS2→partner) and Y-score (partner→RARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	7-methylguanosine mRNA capping →	+0.106	+0.650	<.001	<.001	3	16
OVARY	7-methylguanosine RNA capping →	+0.106	+0.650	<.001	<.001	3	16
BLOOD_Leukemia	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.099	+0.716	<.001	<.001	3	15
BLOOD_Lymphoma	Hair follicle placode formation →	+0.101	+0.798	<.001	<.001	3	14
URINARY_TRACT	Negative regulation of chromosome segregation →	+0.130	+0.842	.002	<.001	3	13
BLOOD_Lymphoma	Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication →	+0.122	+0.916	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,014 associations by consensus.

7-methylguanosine mRNA capping by RARS2 expression — OVARY

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