RARS1

Across TCGA cell cohorts, RARS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,389 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RARS1-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Nuclear division, and Protein localization to nucleus. Each is linked with RARS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RARS1-to-partner and partner-to-RARS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by RARS1-low versus RARS1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RARS1→partner) and Y-score (partner→RARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of rRNA processing →	+0.135	+0.589	<.001	<.001	3	14
BREAST	Nuclear division →	+0.075	+0.763	.001	<.001	3	14
LIVER	Protein localization to nucleus →	+0.064	+0.790	<.001	<.001	3	14
OVARY	Protein localization to kinetochore →	+0.138	+0.646	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	+0.108	+0.625	.007	.004	3	13
PANCREAS	Protein import into nucleus →	+0.077	+0.630	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

Positive regulation of rRNA processing by RARS1 expression — LARGE_INTESTINE

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