Across TCGA pan-cancer cohorts, RARRES2P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RARRES2P4’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RARRES2P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RARRES2P4 is over-expressed in tumor.
KIRP and LUSC are the cancer types where RARRES2P4 tumor–normal differential expression is most reproducible.