RAPSN

Across TCGA patient cohorts, RAPSN mutation is significantly associated with the RNA expression of many other genes, with 1,522 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAPSN-associated genes across cancer lineages are RNA5SP231, MIR7702, and RNU6-147P. Each is linked with RAPSN in more than 2 cancer types. Because this analysis shows association rather than direction, both RAPSN-to-partner and partner-to-RAPSN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP231 grouped by RAPSN-low versus RAPSN-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAPSN→partner) and Y-score (partner→RAPSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNA5SP231 →	+0.264	+7.977	<.001	.007	3	3
UCEC	MIR7702 →	+0.155	+3.668	<.001	.009	3	3
SKCM	RNU6-147P →	+0.328	+4.513	<.001	.009	3	2
LUSC	RNU6-597P →	+0.423	+5.093	<.001	.008	3	2
LUSC	RNU6-823P →	+0.312	+5.978	<.001	.002	3	2
LUSC	RN7SL241P →	+0.144	+5.337	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,522 associations by consensus.

RNA5SP231 by RAPSN expression — LGG

Explore this box plot interactively →