RAPH1

Across TCGA patient cohorts, RAPH1 mutation is significantly associated with the RNA expression of many other genes, with 1,067 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAPH1-associated genes across cancer lineages are LINC01072, BTF3P11, and OR10J6P. Each is linked with RAPH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAPH1-to-partner and partner-to-RAPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by RAPH1-low versus RAPH1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAPH1→partner) and Y-score (partner→RAPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	LINC01072 →	+0.099	+3.976	.003	.001	3	3
BLCA	BTF3P11 →	+0.081	+3.080	.009	.003	3	2
HNSC	OR10J6P →	+0.042	+5.339	<.001	.003	3	2
HNSC	MT-TD →	+0.440	+5.608	<.001	.002	3	2
LIHC	RNA5SP393 →	+0.295	+5.355	<.001	.005	3	2
UCEC	CTLA4 →	+0.532	+1.680	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,067 associations by consensus.

LINC01072 by RAPH1 expression — LUSC

Explore this box plot interactively →